Vitamin D may be involved in etiology of obesity, and its complications, such as hypertension, insulin resistance, and low-grade inflammation. Ī low plasma of 25-hydroxy-vitamin D is commonly seen in obesity. Further evidence for the potential connection between prognosis and RDW is chronic inflammation and even low-intensity inflammation might play a significant role in atherogenesis and platelet activation. RDW may be a new inflammatory biomarker, and a high RDW is reported to be associated with metabolic syndrome (MetS). The RDW, an indicator of a routine blood test, shows the average volume and variety of red blood cells and is usually combined with other clinical indicators to diagnose anemia. Red blood cell distribution width (RDW) is a parameter routinely measured by advanced hematology analyzers. Also, recent animal and human experimental studies have shown that increased WBC and neutrophils counts are potentially related to obesity and are obesity correlated inflammatory markers. The neutrophil to lymphocytes ratio (NLR) is an important inflammatory index affected by health status and lifestyle. Several studies have shown that abdominal obesity may be associated with low-grade of systemic inflammation, which is characterized by an increase in pro-inflammatory cytokines, hematological inflammatory parameters and acute phase proteins such as C-reactive protein (CRP). In the last studies, the prevalence of abdominal obesity in Iran was described to be 52.8% and 44.4% in men and women, respectively. Of great concern is abdominal obesity, one of the most common health issues with increasing incidence in middle-aged people globally. The prevalence of overweight and obesity has increased worldwide in the past five decades, and approximately a third of the world's population is now classified as overweight or obese. Obesity is considered a significant health care problem and is a complex multifactorial condition. Inflammation plays an important role in the progress of chronic diseases such as obesity, cardiovascular disease, type 2 diabetes mellitus and cancer. Conclusionįortification with nano-encapsulated vitamin D 3 of dairy products may decrease inflammation in individuals with abdominal obesity. The values of = neutrophil to lymphocyte ratio (NLR), platelets to lymphocyte ratio, and RDW to platelets ratio (RPR) reduced significantly in the fortification group ( p < 0.05). The results showed that serum levels of neutrophils, lymphocytes, platelets, and RDW before and after intervention in the fortified dairy groups were significantly lower ( p < 0.05). The results showed that serum levels of neutrophils, lymphocytes, platelets and red blood cell distribution width (RDW) were significantly lower before and after the intervention in fortified dairy groups. Simple milk (200 mL/day), low-fat yogurt fortified by 1500 IU nano-encapsulated vitamin D 3 (150 g/day), and simple yogurt (150 g/day). Two hundred and eighty nine subjects were allocated to four groups: low-fat milk fortified by 1500 IU nano-encapsulated vitamin D 3 (200 mL/day). This multi-center study was conducted using a 2.5-month parallel total-blind randomized clinical trial design. The current study aimed to determine the efficacy of low-fat milk and yogurt fortified with 1500 IU nano-encapsulated vitamin D, on systemic inflammation in abdominal obese participants. Vit D deficiency is also associated with increased systemic inflammation. doi:10.The prevalence of vitamin D deficiency is increasing globally and is associated with an increased risk of metabolic syndrome, autoimmune disease, and cardiovascular disease. Dairy consumption in association with weight change and risk of becoming overweight or obese in middle-aged and older women: a prospective cohort study. Rautiainen S, Wang L, Lee IM, Manson JE, Buring JE, Sesso HD. ![]() Body composition and strength changes in women with milk and resistance exercise. Josse AR, Tang JE, Tarnopolsky MA, Phillips SM.Association of dairy intake with body composition and physical function in older community-dwelling women. Radavelli-Bagatini S, Zhu K, Lewis JR, Dhaliwal SS, Prince RL.Calcium supplementation for prevention of primary hypertension. Cormick G, Ciapponi A, Cafferata ML, Belizán JM.The association between osteoporosis and hypertension: The role of a low dairy intake. Varenna M, Manara M, Galli L, Binelli L, Zucchi F, Sinigaglia L. ![]() Dairy products, dietary calcium and bone health: possibility of prevention of osteoporosis in women: the Polish experience. Wadolowska L, Sobas K, Szczepanska JW, Slowinska MA, Czlapka-Matyasik M, Niedzwiedzka E. ![]()
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